Here is a link to an interesting article describing a recent scientific find uncovered by a group of Scientists working at Dusseldorf Universities at Bonn. The studies show that there is a gene variant in the 500, 000 + positions of human genomes that occurs more frequently in bald men than it does in their control study group.
This study essential helps concludes what many Scientists have often surmised - that hair loss is in fact caused by more than one gene, and that the risk gene for an androgen receptor - which is a receptor that is responsible in the direct transcription of gene transcription and in genetic expression - is actually found on Chromosome 20 - which is inheritable from either the paternal or maternal side of the family. The two obvious hormonal candidates are Testosterone and the more potent Dihydrotestosterone, which is a factor in pattern baldness for most men and some women.
Dihydrotestosterone is a hormonal byproduct of Testosterone, and is found in the hair follicles, testes, prostate gland and adrenal gland. The conversion of Testosterone to DHT is incurred by way of the enzyme 5-alpha reductase. The resultant DHT binds to the hair follicle and causes both follecular deterioration and miniaturization.
What is most interesting about the findings of the study is that the research brings to light a possible alternative to limiting Testosterone or the effects of 5-alpha reductase as popular methods for hair loss treatment. Perhaps Science will find a way to limit the expression of these genetic variations and limit hair loss entirely?
At the same time, this brings an ethical and cautious matter to light. Since hair loss is not a medical danger to the patient, should this type of research be promoted? Are there ethical boundaries we need to consider before plunging forward in genetic science, especially when dealing with non life-threatening events and beauty?
What are your thoughts?
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